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We measured the volumes of the entire length of temporal lobe and hippocampal formation from coronal images in 29 healthy young adults to take into account normal side-to-side variation.Although whole-brain, temporal lobe,and left hippocampal volumes were significantly smaller in women,normalizing measurements for the whole brain eliminated intersex temporal lobe and hippocampal differences.There was a weak but significant inverse correlation between age and normalized hippocampal,but not temporal lobe or whole-brain,volume.In contrast to previous studies,we found no significant side-to-side differences in the sizes of temporal lobes or hippocampi.When performing MR volumetry,it is important to include the entire length of the hippocampal formation. |
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